
Human Metapneumovirus (HMPV) is a respiratory virus that has recently garnered attention due to a surge in cases, particularly in China. First identified in 2001, HMPV is known to cause respiratory infections, especially in young children, the elderly, and immunocompromised individuals. This article delves into the origins of HMPV, its symptoms, transmission, and the current global situation.
Emergence of HMPV
HMPV was first discovered in the Netherlands in 2001. It is a negative-sense single-stranded RNA virus belonging to the Pneumoviridae family and is closely related to the avian metapneumovirus. Since its discovery, HMPV has been recognized as a common cause of respiratory infections worldwide.

Recent Outbreaks Post-COVID-19
In late 2024, China experienced a significant increase in HMPV cases. Data from the Chinese Center for Disease Control and Prevention indicated that HMPV was linked to 6.2% of positive respiratory illness tests and 5.4% of respiratory-related hospitalizations during the week of December 16 to 22, 2024. This surge surpassed infections from COVID-19, rhinovirus, and adenovirus during the same period. Health officials noted that the rise in cases was consistent with typical seasonal trends.
Following the outbreak in China, neighboring countries reported increases in HMPV cases. Malaysia, for instance, recorded 327 cases in 2024, up from 225 in 2023. The Malaysian Ministry of Health urged the public to remain vigilant, emphasizing preventive measures such as mask-wearing and good hygiene practices.
In the United Kingdom, as of January 13, 2025, one in 20 hospital patients tested for respiratory infections was found to have HMPV. While this was the highest level recorded that winter, it was less than half the peak observed at the end of 2021.
Symptoms and Transmission
HMPV typically causes symptoms similar to the common cold, including:
- Cough
- Fever
- Runny or stuffy nose
- Sore throat
- Wheezing
- Shortness of breath
In severe cases, especially among infants, the elderly, and those with weakened immune systems, HMPV can lead to bronchitis or pneumonia. The virus spreads through respiratory droplets when an infected person coughs or sneezes, as well as through direct contact with contaminated surfaces.

Prevention and Treatment
Currently, there is no specific antiviral treatment or vaccine for HMPV. Management focuses on relieving symptoms, which may include:
- Rest
- Hydration
- Over-the-counter medications to alleviate fever and pain
Preventive measures are crucial to reduce the spread of HMPV:
- Regular handwashing with soap and water
- Using hand sanitizers when soap and water are unavailable
- Avoiding close contact with individuals exhibiting respiratory symptoms
- Wearing masks in crowded or poorly ventilated areas
- Covering mouth and nose with a tissue or elbow when coughing or sneezing
These measures are especially important during peak seasons for respiratory infections.

Global Impact and Current Situation
While the recent surge in HMPV cases has raised concerns, health authorities emphasize that this virus is not new and behaves in line with known seasonal patterns. The World Health Organization has not declared HMPV a global health emergency, noting that current infection levels are within expected ranges for the winter season.
In Pakistan, HMPV has been present since 2001, with sporadic cases reported over the years. The National Institute of Health has confirmed its presence and continues to monitor the situation closely. As of early 2025, there has been no significant surge in cases within the country.
Conclusion
Human Metapneumovirus is a well-established respiratory pathogen that resurfaces seasonally, causing mild to severe respiratory illnesses. The recent increase in cases, particularly in China, aligns with expected seasonal trends and does not indicate a novel outbreak. Maintaining standard preventive measures and staying informed through reputable health sources remain the best strategies to manage and mitigate the impact of HMPV.